International

Would an attack from Iran deplete the U.S. arsenal of interceptor missiles?

Hoang Bach March 3, 2026 10:48

The fact that U.S. forces have repeatedly shot down hundreds of Iranian ballistic missiles in recent days is raising serious questions about the sustainability of the country's air defense arsenal. With the conflict predicted to last for weeks, Washington is facing a difficult dilemma between the rapid depletion of expensive weapons and limited production capacity.

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US Defense Secretary Pete Hegseth and Chairman of the Joint Chiefs of Staff General Dan Caine answered questions from the press regarding the military operation in Iran at a press conference at the Pentagon (Washington, DC) on March 2nd. In recent days, the US military has launched airstrikes on hundreds of targets in Iran, while Israel has also expanded its offensive into Lebanese territory. Photo: AFP

The race between launch platforms and anti-aircraft missiles.

Since the outbreak of hostilities, U.S. forces have successfully intercepted hundreds of ballistic missiles targeting U.S. and partner bases to maintain regional stability, according to General Dan Caine, a senior U.S. military official, on March 2. While these interceptions have been a resounding tactical success in preventing enemy missiles from reaching their targets, they have come at a very high cost: a significant depletion of the already scarce stockpile of high-tech interceptor missiles.

Kelly Grieco, a senior fellow at the Stimson Center, warns of the imminent risk that the U.S. and its partners could run out of interceptor missiles before Iran uses up its entire stockpile of offensive missiles.

According to initial Israeli estimates, Tehran possesses approximately 2,500 ballistic missiles – a number almost certainly far exceeding the total number of ballistic missile interceptors currently in the possession of the United States and Israel.To counter this disparity, the US-Israel coalition is aggressively hunting down the enemy's launch platforms and weapons depots. According to Grieco, the current conflict is essentially a fierce race between Iran's launch systems and the speed of US-Israeli bombing to neutralize the source of those attacks.

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Trails of smoke from missiles fill the sky over the coastal city of Tel Aviv (Israel) during Iran's latest attack on March 3. Photo: AFP

Time pressure and resource management

Besides ballistic missiles, General Caine acknowledged that Iran's unmanned aerial vehicles (UAVs) also pose a significant threat.While not disclosing the exact number shot down, he asserted that the US air defense system had proven its effectiveness and ability to respond swiftly to these platforms.

However, experts believe the most serious shortage lies in the area of ​​ballistic missile interceptors, because the expenditure of expensive weapons to destroy UAVs is not as high.

A key factor determining the number of interceptor missiles needed is the duration of the conflict. U.S. President Donald Trump has previously mentioned a military operation lasting weeks, but he recently asserted that progress is currently far exceeding initial projections.

Although the initial estimate was around 4 to 5 weeks, Trump emphasized that Washington had the capacity to sustain the war for much longer. Meanwhile, Defense Secretary Pete Hegseth also left open various timeframes, ranging from 2, 4 to 6 weeks depending on developments on the ground.

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Smoke trails from interceptions by the Iron Dome missile defense system illuminate the skies over Jerusalem on March 1st. The image reflects the escalating tensions in the Middle East following US and Israeli airstrikes against Iran on February 28th, which resulted in the death of the country's Supreme Leader. In retaliation, Tehran launched a barrage of missiles targeting Israeli territory and Gulf states. Photo: AFP

Threat to Washington's global defense strategy

The repercussions of this conflict are not limited to the Middle East but also risk weakening the United States' global standing. Joe Costa, Director of the Defense Program at the Atlantic Council, argues that a protracted war with Iran could deplete the crucial stockpile of anti-aircraft missiles that the U.S. needs to allocate to other priority regions around the world.The outcome of this risk depends entirely on how effectively the United States and Israel neutralize Tehran's missile and UAV launch capabilities.

Looking at the bigger picture, expert Grieco points out a harsh reality: the current rate of weapons production cannot keep up with actual demand. From Europe and the Indo-Pacific to the Middle East, every battlefield is experiencing a "thirst" for launch systems and anti-aircraft missiles. Meanwhile, Washington is simply consuming them at a much faster rate than its defense industry can compensate.

Hoang Bach