Predicted lineup for MU vs Ipswich Town: Patchwork defense
The Standard predicts MU's starting lineup in the first match under coach Ruben Amorim, with changes in midfield and defense.
Coach Ruben Amorim will officially debut for Manchester United in the away match at Ipswich in the 12th round of the Premier League. After three weeks of waiting since being appointed to replace coach Erik ten Hag, the Portuguese strategist will have the opportunity to show his new playing style with the team.

Mainoo replaces Casemiro, Ugarte starts
One of the notable changes to the expected line-up for United is the introduction of Kobbie Mainoo in central midfield instead of Casemiro. Mainoo, who has not played since the beginning of October due to injury, is expected to partner Manuel Ugarte in the midfield. Ugarte, a former student of Amorim at Sporting Lisbon, will be one of the key players in the starting lineup.
This means that Casemiro, despite his improved form under interim boss Ruud Van Nistelrooy, will have to sit on the bench. Coach Amorim has informed the Brazilian midfielder that he should look for a new destination in the January transfer window.
Defensive crisis
Despite having six centre-backs in the squad, United are facing an injury crisis. Lisandro Martinez and Victor Lindelof are both out with fitness issues, while Harry Maguire is yet to return. Young centre-back Leny Yoro, although back in training, is unlikely to start due to his long absence.

In this situation, coach Amorim may be forced to use a trio of central defenders including Diogo Dalot, Matthijs De Ligt and Jonny Evans. However, The Standard believes that Martinez can recover in time to be in the starting lineup.
On the right wing, Amad Diallo is likely to be in the starting lineup. The 22-year-old has impressed Amorim in recent training sessions and is expected to continue to shine. Up front, Marcus Rashford is expected to take on the role of "number 9" striker, as Rasmus Hojlund and Joshua Zirkzee have both failed to live up to expectations.
Predicted starting lineup of MU
The Standard newspaper gives the predicted lineup of MU in the debut match of coach Amorim:
Starting lineup:
Onana; Dalot, De Ligt, Martinez; Amad, Mainoo, Ugarte, Mazraoui; Fernandes, Garnacho; Rashford.