A miracle: Sperm is created from skin cells.
Scientists say they have achieved initial success in creating sperm from skin cells, hailed as a medical breakthrough that could help treat infertility.
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Photo: Telegraph. |
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"What should be done when a couple longs to have a child but lacks gametes (eggs or sperm)?" asks Carlos Simon, scientific director of the Valencia Institute for Infertility, Spain's first assisted reproductive technology facility. "The issue we want to address is creating gametes in people who don't have them."
This research was inspired by previous discoveries by Shinya Yamanaka (Japan) and John Gordon (UK), who jointly won the Nobel Prize in 2012 for finding the mechanism that transforms mature cells into embryonic stem cells. Later, Simon and his research team reprogrammed mature skin cells by finding the mixture of genes necessary to produce gametes.
Within a month, the team had found skin cells and transformed them into a stem cell that could develop into a sperm or egg, but not yet capable of fertilization. "This is a sperm, but it needs a further maturation phase to become a gamete. This is just the beginning," Simon said.
Earlier this year, Chinese researchers announced they had created mice from artificial sperm, marking a further breakthrough in the research of life reconstruction. "With humans, we have to do much more experimentation because we're talking about the birth of a child," Simon said.
According to VNE
