Cagliari vs Lazio Prediction - Serie A: A Challenge at Unipol Domus

At 02:45 on February 22, 2026, the Unipol Domus stadium will witness a clash between Cagliari and Lazio in Serie A. This is an important match for both teams as they strive to improve their position in the middle of the league table.

Current league position and form

Lazio are currently ranked 10th with 33 points after 25 matches played. The capital team's recent form has been inconsistent, with 1 win, 2 draws, and 2 losses in their last 5 matches. Their goal difference is balanced, with 26 goals scored and 25 goals conceded.

Conversely, Cagliari sits in 13th place with 28 points. Despite their lower ranking, the home team is showing significant improvement, having won 3 of their last 5 matches. After 25 rounds, Cagliari has scored 28 goals, but their defense remains a concern, having conceded 35 goals.

Head-to-head history: Lazio completely dominates.

Historical data strongly favors the away team. In the last five encounters from the end of 2023 to the present, Lazio has won all five matches, scoring a total of 10 goals and conceding only 3 against Cagliari. The most recent result was in November 2025, when Lazio defeated their opponent 2-0 at home.

Severe manpower crisis

Both coaches are facing a difficult personnel dilemma due to a wave of injuries sweeping through their squads.

Cagliari will be missing several key players.

The home team will be without striker A. Belotti due to a knee injury. The list of absentees continues with G. Borrelli (thigh injury), A. Deiola, M. Felici, M. Folorunsho (knee injuries), and G. Gaetano. The significant personnel shortages in both attack and midfield will pose a major challenge to Cagliari's ambitions of securing points.

Lazio suffers a blow to their defense.

On the other side of the pitch, Lazio also lost some key players. Center-back S. Gigot and veteran Pedro are both absent due to ankle injuries. In addition, T. Basic, M. Gila (knee injury) and M. Lazzari (calf injury) are also unavailable for this trip.

Analysis and prediction of results

Although the head-to-head history heavily favors Lazio, Cagliari's home form and recent winning streak are factors that cannot be overlooked. Lazio have often struggled to score goals this season, with an average of only 1.0 goal per game.

Experts predict a close match. Cagliari's chances of winning or at least drawing are considered higher based on their current form. Predicted odds show Cagliari's chances of winning at 35%, a draw at 35%, and Lazio winning at 30%.

Predicted result:Cagliari win or draw.

Team lineup updated at 02:15 on 22/02/2026

Official lineup

Cagliari

Diagram: 3-5-2

CoachFabio Pisacane

Starting lineup:

• 1. Elia Caprile (G)
• 32. Zé Pedro (D)
• 26. Yerry Mina (D)
• 22. Alberto Dossena (D)
• 2. Marco Palestra (M)
• 25. Ibrahim Sulemana (M)
• 8. Michel Adopo (M)
• 4. Luca Mazzitelli (M)
• 33. Adam Obert (M)
• 9. Semih Kılıçsoy (F)
• 94. Sebastiano Esposito (F)

Substitutes:

• 12. Alen Sherri
• 24. Giuseppe Ciocci
• 28. Gabriele Zappa
• 15. Juan Rodríguez
• 18. Othniël Raterink
• 3. Riyad Idrissi
• 27. Joseph Liteta
• 20. Agustín Albarracín
• 30. Leonardo Pavoletti
• 31. Paul Mendy
• 37. Yael Trepy

Lazio

Diagram: 4-3-3

CoachMaurizio Sarri

Starting lineup:

• 94. Ivan Provedel (G)
• 77. Adam Marušić (D)
• 25. Oliver Provstgaard (D)
• 13. Alessio Romagnoli (D)
• 3. Luca Pellegrini (D)
• 21. Reda Belahyane (M)
• 6. Nicolò Roosevelt (M)
• 24. Kenneth Taylor (M)
• 18. Gustav Isaksen (F)
• 27. Daniel Maldini (F)
• 10. Mattia Zaccagni (F)

Substitutes:

• 55. Alessio Furlanetto
• 40. Edoardo Motta
• 23. Elseid Hysaj
• 4. Patric
• 17. Nuno Tavares
• 7. Fisayo Dele-Bashiru
• 28. Adrian Przyborek
• 32. Danilo Catalli
• 14. Tijjani Noslin
• 22. Matteo Cancellier
• 20. Petar Ratkov
• 19. Boulaye Dia