Analysis and prediction for Lyon vs MU: The Red Devils will struggle to defend.
The Europa League match between Lyon and Manchester United will take place at 2:00 AM on April 11th. Nghe An Newspaper analyzes the teams' form, provides football commentary, and predicts the score.

Latest information on the Lyon vs MU squad
Lyon suffered a major blow ahead of Thursday's match when winger Ernest Nuamah sustained an anterior cruciate ligament (ACL) injury just seven minutes into last week's win against Lille and will be out for the rest of the season. Malick Fofana is also unavailable due to a knee injury.
Nuamah has been replaced by Rayan Cherki – a player being pursued by several big clubs, who has scored 9 goals and provided 18 assists in 36 games this season – including 8 assists in the Europa League. He is likely to continue starting alongside Thiago Almada and one of the two strikers Lacazette or Georges Mikautadze in attack.
Former Manchester United midfielder Nemanja Matic will partner Corentin Tolisso and Tanner Tessmann in midfield. Meanwhile, Ainsley Maitland-Niles – a former Arsenal player – will occupy the right-back position, alongside Clinton Mata, Moussa Niakhate, and either Nicolas Tagliafico or Abner Vinicius in defense.
On the Manchester United side, Lisandro Martinez (knee), Amad Diallo, Ayden Heaven (ankle) and Jonny Evans (back) remain absent due to injury. Matthijs de Ligt (ankle) and Kobbie Mainoo (calf) will be assessed before the match, with Mainoo having returned to training.
Luke Shaw is ready to play after a four-month absence due to a hamstring injury, but Patrick Dorgu is likely to retain his left-back position. Harry Maguire could still start in central defense despite leaving the game early in the Manchester derby.
Mason Mount could also feature, playing in either midfield or attack. Alejandro Garnacho is likely to remain in attack, despite having scored only one goal in his last 27 games. Amorim will consider whether to continue using Rasmus Hojlund or give Joshua Zirkzee a chance to return to the team.
Latest predicted lineups for Lyon vs MU
Lyon:
Perri; Maitland-Niles, Mata, Niakhate, Tagliafico; Tessmann, Matic; Cherki, Tolisso, Almada; Mikautadze
Manchester United:
Onana; Mazraoui, Maguire, Yoro; Dalot, Ugarte, Casemiro, Dorgu; Fernandes, Garnacho; Zirkzee
Latest football match prediction: Lyon vs MU
Five days after their 0-1 defeat to Nottingham Forest in the Premier League, Man United continued to disappoint with a goalless draw against city rivals Manchester City at Old Trafford on Sunday – a dull match where neither team made any significant impact.

Ruben Amorim believes fans shouldn't expect a derby as dramatic as in the past, as both Manchester teams – red and blue – are currently struggling. However, Red Devils fans still expect more from a team that Amorim claims is "improving".
Securing a European spot through the Premier League is now a nearly impossible goal for Man United. They sit 13th in the table with just 38 points from 31 games, seven points behind the top half, and are on track for their worst season in the league's history.
Nevertheless, glory in the Europa League remains achievable. Man United are currently the only team undefeated in the competition this season (6 wins, 4 draws), most recently a 5-2 aggregate victory over Real Sociedad in the round of 16. Captain Bruno Fernandes scored a hat-trick in the 4-1 second leg win last month.
More broadly, Man United have lost only one of their last 21 Europa League matches – a 0-3 defeat to Sevilla in April 2023, which was also the only time they failed to score in that run. They are also unbeaten in their last 11 first-leg knockout matches in European competitions, since their 0-1 defeat to Barcelona in the 2019 Champions League.
Since a run of seven winless matches across all competitions between mid-January and early February, Lyon have won seven of their last ten games, including six wins in their last seven appearances, scoring a total of 19 goals.
Following their 2-4 defeat to Strasbourg in Ligue 1, Lyon quickly bounced back with a 2-1 home win against Lille on Saturday. Alexandre Lacazette and Rayan Cherki scored the goals, helping the home team come from behind to secure all three points.
Despite head coach Paulo Fonseca serving a nine-month touchline ban for reacting to a referee, assistant coach Jorge Maciel is still effectively leading the team from the dugout. Lyon currently sits fifth in Ligue 1, just two points behind the top three – a position that guarantees direct Champions League qualification – with six rounds remaining.
Lyon finished sixth in their Europa League group of 36 – three places below Man United – but then thrashed FCSB 7-1 on aggregate in the round of 16. They are now aiming for their first semi-final appearance in a major European competition since the 2019–2020 Champions League.
However, Lyon have never beaten Man United in their previous four encounters. They took the lead but were pegged back in both home matches: a 2-2 draw in September 2004 and a 1-1 draw in February 2008. Lyon are also the only French team behind Barcelona in terms of winless matches against them in Europe (8 winless games against Barca). Furthermore, they have lost all three of their most recent matches against English opponents.
Latest Lyon vs MU score prediction
Based on the above football analysis, we and leading football websites worldwide have provided our predictions for the match.Lyon vs MUas follows:
- Sportsmole:Lyon 1-1 MU
- WhoScore:Lyon 1-2 MU
- Our newspaper predicts:Lyon 1-1 MU
When and where can I watch Lyon vs MU live?
To watch the Lyon vs MU match live in the Europa League, taking place at 2:00 AM on April 11th, viewers can tune in to the following channels:K+ Sport,K+PMor online sports channels. We hope you enjoy watching football.


