Inter vs Pisa Prediction - Serie A: A significant difference in class at Giuseppe Meazza

At 2:45 AM on January 24, 2026, the Stadio Giuseppe Meazza will witness a clash between two completely opposite extremes in Serie A: Inter Milan, the team currently sitting at the top of the table, and Pisa, a team struggling in the relegation zone at 19th place.

The absolute dominance of the top team.

Inter are showing incredible consistency in this season's Serie A campaign. With 49 points after 21 rounds, Simone Inzaghi's team maintains their top position thanks to their well-rounded attacking and defensive play. Statistics show that the team has scored 44 goals (an average of 2.1 goals per game) and conceded only 17, a figure that demonstrates an extremely smooth-running system.

At their home ground, Giuseppe Meazza, Inter are virtually unbeatable, with 8 wins in their home matches. Their form in their last 5 games is incredibly impressive, with 4 wins and 1 draw. Inter's ability to control the game and impose their style of play is expected to put immense pressure on the opposing defense from the very first minutes.

Pisa and the difficult relegation battle.

In stark contrast to the home team's resurgence, Pisa is experiencing a difficult season. Ranked 19th with only 14 points, Pisa has only managed one win since the start of the season. Their only bright spot is their ability to hold opponents to a draw, with 11 draws, including 7 away games.

However, Pisa's attack is a major problem, having scored only 16 goals in 21 matches. With an average of less than one goal per game, it will be very difficult for the visitors to penetrate Inter's solid defense. Meanwhile, their defense has conceded 31 goals, and facing an Inter team with top-class strikers will be an extreme challenge for the visitors.

The balance of power and history of confrontations.

In terms of personnel, Inter will be missing several key players. H. Calhanoglu is sidelined with a calf injury, while D. Dumfries is absent due to an ankle injury. Additionally, the availability of R. Di Gennaro and T. Palacios remains uncertain. However, with their current squad depth, Inter are still considered the clear favorites.

On the other side of the battlefield, Pisa traveled to Milan with a long list of injured players. Key names like R. Albiol, J. Cuadrado, Mateus Lusuardi, and C. Stengs were all absent due to various injuries. The absence of Albiol's experience and Cuadrado's potential for surprise attacks made Pisa's chances of causing an upset slimmer than ever.

Recent head-to-head history also favors the blue-and-black striped team. In their most recent encounter in November 2025, Inter comfortably defeated Pisa 2-0 away from home.

Match analysis

Based on current statistics and strength, Inter holds a clear advantage with a predicted win rate of up to 50%, while Pisa's chances of winning are considered almost zero. Although Pisa might try to aim for a draw to accumulate points in the relegation battle, Inter's superior class and home advantage will most likely help them secure all three points and continue their climb up the standings.