Detecting genetic factors helps detect ovarian cancer early

Women who inherit a faulty BRIP1 gene are three times more likely to develop ovarian cancer than other women.

This is the result of a new study published in the Journal of the National Cancer Institute of America on January 19.

To reach the above conclusion, scientists at the US National Cancer Institute compared the genetic samples of more than 8,000 European women, including women diagnosed with ovarian cancer, a healthy group and a group with a family history of the disease.

The study results showed that the rate of malignant cancer diagnosis was higher in the group of women with BRIP1 disorder, and the disease was also diagnosed at an older age and at a later stage.

Specifically, normally, 18 out of 1,000 women will get ovarian cancer. This rate increases to 58/1,000 for the group of women who unfortunately inherit the faulty BRIP1 gene. These errors cause tissue cells to no longer function effectively to repair themselves, leading to long-term genetic damage and eventually leading to cancer.

Ovarian cancer is a rare disease but has a high mortality rate, and is difficult to detect early. Currently, ovarian cancer is in the group of 7 common cancers in women.

In 2012 alone, approximately 239,000 cases were diagnosed with the disease worldwide.

The disease is often detected at a late stage, making treatment less effective. About 60% of patients die within the first 5 years of the disease. To date, there are no standards or testing methods to help detect this disease early.

Therefore, the above research opens up hope for a gene testing method that helps detect and treat early to improve treatment effectiveness and prolong life for ovarian cancer patients./.

According to VIETNAM+