Fruits that are toxic when taken with medicine

When you are sick and have to take medicine, you need to know the interactions between certain fruits and the medicine you are taking to avoid eating them, otherwise you will encounter many dangers.

Eating fruit is very good for your health, especially when you are sick because it provides many vitamins and minerals for the body. However, when you are sick and have to take medicine, you need to know the interactions between certain types of fruit and the medicine you are taking to avoid eating them, otherwise you will encounter many dangers.

Taking blood pressure medication and eating grapes: Easy to be hospitalized

The blood pressure medications at the center of this conflict are calcium channel blockers such as nifedipine and verapamil. These two drugs work by blocking calcium channels, preventing calcium from entering the smooth muscle system of the blood vessels.

Without calcium, muscles cannot contract and therefore blood pressure is lowered. The drug has the effect of treating blood pressure and is one of the drugs that is widely used for patients. But if you take this drug and eat grapes, be careful, the possibility of hospitalization is very high. Because grapes increase the risk of drug poisoning or overdose.

The reason is that grapes contain inhibitors of the enzyme CYP3A4, a member of the group of drug-metabolizing enzymes. When grapes are present, the drug accumulates and is eliminated more slowly. Therefore, the patient is at risk of increasing the concentration of the drug in the body when taking a second dose while the first dose has not yet been completely metabolized.

It has been tested and found that grapes can accumulate and increase the concentration of drugs by about 40% compared to drinking with plain water. Therefore, patients are at risk of drug poisoning or experiencing unwanted side effects.

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Taking beta blockers and eating apples: "No more blockers"

Beta blockers are drugs that inhibit beta receptors in the cardiovascular system. Using these drugs will help us control many diseases such as high blood pressure, tachycardia, and vascular headaches. They are also basic drugs in cardiovascular drugs.

However, if you take this group of drugs and eat apples indiscriminately, the treatment goal cannot be successful. The underlying cause lies in the active substance in apples. Apples contain chemicals that inhibit the activity of a transport polypeptide called OATP.

OATP is an important polypeptide located on the intestinal membrane that plays a role in transporting drugs to the surface cells and absorbing them into the blood. The presence of apples or apple juice prevents this polypeptide from performing its role.

As a result, absorption of the drug is limited. Blood levels of the drug are reduced and this is why beta blockers are not effective. The drugs affected are celiprolol and talinolol.

In addition to apples, oranges and grapefruits are also similar fruits. Therefore, they should be avoided when using beta blockers to treat blood pressure and cardiovascular diseases...

Taking stomach medicine and eating sour fruit: Ulcer completely ulcerated

If you take stomach medicine and eat sour foods and fruits like pineapple, tamarind, orange, lemon... then it is considered as zero, especially when taking acid-reducing drugs. Because acid-reducing drugs are used in treatment to reduce acid secretion in the stomach to a minimum level, preventing the destruction of ulcers. Acid is considered a corrosive substance and the substance that causes ulcers.

While anti-secretory drugs reduce acid intake, sour foods increase acid intake. This is like "beating the drum one way and blowing the trumpet the other", ulcers remain ulcers. Therefore, people with long-term stomach ulcers should definitely not eat sour foods while taking medication.

According to Alobacsi.vn